Global Health/Biotechnology
Janus Henderson Global Life Sciences Fund
Last updated: 2026-09-03
The Verdict
Janus Henderson Global Life Sciences Fund charges an expense ratio of 0.81%. On a $100,000 portfolio, that's $810 per year in fees, and it scales with the amount invested. Supreme.PM's decoded model tracked it at 99% correlation, for a flat monthly subscription that does not change with portfolio size.
Expense Ratio
0.81%
Star Rating
4/ 5
Market Beta
0.99
Model Correlation
99%
Sharpe Ratio
0.50
Max Drawdown
24.75%
Supreme.PM Cost
Flat monthly subscription
Not a percentage of your assets
Performance
Performance comparison — 1Y: Fund 40.2% vs Model 38.7%; 3Y: Fund 51.7% vs Model 51.8%; 5Y: Fund 56.3% vs Model 50.2%.
Alpha After Fees
Supreme.PM's model achieves 99% correlation with Janus Henderson Global Life Sciences Fund, providing similar exposure at a flat subscription cost.
Fee Analysis
Janus Henderson Global Life Sciences Fund charges 0.81% of assets annually. Supreme.PM charges a flat monthly subscription instead, so its cost does not rise as a portfolio grows.
Data sources: Refinitiv Lipper, SEC EDGAR Filings, Supreme.PM Analytics
Past performance does not guarantee future results. Model returns are backtested and may not reflect actual trading conditions.
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Frequently Asked Questions
What is the expense ratio of Janus Henderson Global Life Sciences Fund?
Janus Henderson Global Life Sciences Fund has an expense ratio of 0.81%, charged as a percentage of the amount invested. Supreme.PM's decoded model is offered for a flat monthly subscription instead.
How does Supreme.PM replicate Janus Henderson Global Life Sciences Fund?
Supreme.PM builds a transparent, rules-based model of listed securities designed to track this fund's return profile. Over the measured period it tracked the fund closely, at 99% correlation. The model is published in full, so its positions are visible rather than disclosed with a delay.
What are the risks of fund replication?
While our models aim for high correlation, they may not perfectly match the fund's returns due to timing differences in rebalancing, transaction costs, and disclosure delays. Backtested results may not reflect future performance.
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